A career as rich as Willem Dafoe's puts the "random" in the A.V. Club's Random Roles feature, but I touched on as many high (and low) points as time would allow in an interview on the occasion of two new movies: Abel Ferrara's 4:44 Last Day on Earth and the upcoming The Hunter. More from Dafoe, including lots on Antichrist and a bit on Spider-Man, in our previous interview.
UPDATE: Forgot I talked to Dafoe in 2001, for Shadow of the Vampire. That's here.